Mixed-integer quadratic problem are solved just like standard QP problem, but with a subset of the variables assigned to the binary/integer domain.
toms integer x
toms y
objective = -6*x + 2*x^2 + 2*y^2 - 2*x*y;
constraints = {x+y<=1.9, x>=0, y>=0};
solution = ezsolve(objective,constraints);